Environmental Risk Assessment for the Active Pharmaceutical Ingredient Mycophenolic Acid in European Surface Waters
نویسندگان
چکیده
منابع مشابه
An Environmental Risk Assessment for Human-Use Trimethoprim in European Surface Waters.
An environmental risk assessment (ERA) for the aquatic compartment in Europe from human use was developed for the old antibiotic Trimethoprim (TMP), comparing exposure and effects. The exposure assessment is based on European risk assessment default values on one hand and is refined with documented human use figures in Western Europe from IMS Health and measured removal in wastewater treatment ...
متن کاملUse of Pat for Active Pharmaceutical Ingredient Crystallization Process Control
Crystallization of active pharmaceutical ingredient (API) or pharmaceutical drug substances is a crucial unit operation. In this paper challenges and scientific progress over the last two decades in the areas of pharmaceutical crystallization thermodynamics, kinetics, polymorphism, process modeling, and process control were attempted. Effective utilization of such scientific knowledge for optim...
متن کاملHypochlorous Acid as Active Ingredient
on the bacterial viability of S. mutans, A. israelii, P. gingivalis, A. actinomycetemcomitans, E. corrodens, C. rectus, K. oxytoca, K. pneumoniae and E. cloacae. The percentage of live bacteria was tested by fluorescence method using Live/Dead kit® and BacLight (Molecular Probes®) and compared between groups by the Kruskal-Wallis and U Mann-Whitney tests with Bonferroni correction (p value<0.01...
متن کاملTregitope Peptides: The Active Pharmaceutical Ingredient of IVIG?
Five years ago, we reported the identification and characterization of several regulatory T-cell epitopes (now called Tregitopes) that were discovered in the heavy and light chains of IgG (De Groot et al. Blood, 2008). When added ex vivo to human PBMCs, these Tregitopes activated regulatory T cells (Tregs), increased expression of the transcription factor FoxP3, and induced IL-10 expression in ...
متن کاملStable isotopic composition of the active pharmaceutical ingredient (API) naproxen.
A survey of the multi-stable isotopic composition of an active pharmaceutical ingredient (API), naproxen, was performed to assess the potential of Isotope Ratio Mass Spectrometry (IRMS) to distinguish the provenance of APIs. Twenty-six lots of naproxen from six manufacturers representing four countries (Italy, India, Ireland, and the USA) were analyzed for three isotope ratios (13C/12C, 18O/16O...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Environmental Toxicology and Chemistry
سال: 2019
ISSN: 0730-7268,1552-8618
DOI: 10.1002/etc.4524